Project chAnGE:

Accelerating changes in clinical practice to combat NCDs and support healthy ageing

Project chAnGE: accelerating changes in clinical practice to combat NCDs and support healthy ageing


Every two seconds, someone dies prematurely from noncommunicable diseases (NCDs).  It’s time to make a difference.

Project chAnGE was set up under the European Innovation Partnership on Active & Healthy Ageing (EIP on AHA), in collaboration with Upjohn, a Pfizer division. It aims to foster changes in clinical practice that can help to combat NCDs and support healthier ageing

EIP on AHA was launched by the European Commission in 2011 to foster innovation and digital transformation in the field of active and healthy ageing. Almost one fifth of the European population is over 65 and this will rise to nearly a quarter by 2030.

Project chAnGE has brought together leading experts in medicines adherence, integrated care and prevention of functional decline; specifically, it has provided grant funding to five projects in Europe to power evidence-based shifts in care. These independent grants have been provided by Upjohn, a division of Pfizer focused on the global fight against NCDs.

About NCDs

According to the WHO, “non-communicable diseases (NCDs) also known as chronic diseases, tend to be of long duration and are the result of a combination of genetic, physiological, environmental and behaviours factors. The main types of NCDs are cardiovascular diseases (like heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructive pulmonary disease and asthma) and diabetes.”


Alessandro Monaco, topic group leader at EIP on AHA, and Shaantanu Donde, Senior Director, Medical Affairs at Upjohn, have co-authored an op-ed in Politico outlining the challenges that Project chAnGE is addressing, and the response that Upjohn and the EIP on AHA are making together.

In November 2019, authors involved in Project chAnGE EIP on AHA have also published an article in the journal Aging Clinical & Experimental Research, “Information and communication technology for increasing healthy ageing in people with non-communicable diseases: identifying challenges and further areas for development.” In May 2019, a broader group of authors published an article examining the impact of COVID-19 on patients with NCDs and healthy ageing in the same journal: “The potential longterm impact of the COVID19 outbreak on patients with noncommunicable diseases in Europe: consequences for healthy ageing".

As noted by Amrit Ray, Upjohn Global President for R&D and Medical, “By funding projects across Europe that facilitate healthy ageing and reduce the burden of NCDs, Project chAnGE will advance research that can drive improved outcomes for patients.”

The five projects supported by Project chAnGE are: